Publications by authors named "E Paixao"
Tuberculosis (TB) is a disease caused by the bacterium and despite effective treatments, still affects millions of people worldwide. The advent of new treatments has not eliminated the significant challenge of TB drug resistance. Repeated and inadequate exposure to drugs has led to the development of strains of the bacteria that are resistant to conventional treatments, making the eradication of the disease even more complex.
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- Post-term pregnancy, reaching or exceeding 42 weeks of gestation, is linked to negative birth outcomes, and while high-income countries often induce labor, low- and middle-income countries lag behind.
- The study aims to examine the prevalence of post-term births, associated risk factors, and their connections to small-for-gestational-age (SGA) neonates and infant mortality in middle-income settings like Brazil, Mexico, and Palestinian refugees.
- Analyzing over 45 million live births, the research found that post-term deliveries significantly increased the risk of SGA neonates and infant mortality, suggesting the need for induction strategies to address these issues.
Background: In utero exposure to infections might set the stage for a chain of events leading to a wide spectrum of long-term health outcomes observed in children and adolescents. This proposal aims to investigate whether syphilis, zika, dengue and chikungunya during pregnancy can increase the risk of the offspring developing a non-infectious chronic condition during childhood and adolescence.
Objectives: 1) Estimate the risk of non-infectious chronic conditions associated to syphilis, zika, dengue and chikungunya during pregnancy and when appropriate, explore if the risk varies by timing during pregnancy when the infection is acquired (first, second or third trimester) and severity (such as severe or mild dengue); 2) Investigate whether in uterus exposure to maternal infection affects the growth pattern of children and adolescents; 3) Examine the extent to which the relationship between maternal infection and non-infectious chronic outcomes are mediated by intrauterine growth restriction and preterm birth.
Background: Pregnancy represents a critical window of vulnerability to the harmful effects of air pollution on health. However, long-term consequences such as risk of having lower respiratory tract infections (LRTIs) are less explored. This systematic review aims to synthesize previous research on prenatal exposure to ambient (outdoor) air pollution and LRTIs in childhood and adolescence.
View Article and Find Full Text PDFBackground: Ethno-racial inequalities are critical determinants of health outcomes. We quantified ethnic-racial inequalities on adverse birth outcomes and early neonatal mortality in Brazil.
Methods: We conducted a cohort study in Brazil using administrative linked data between 2012 and 2019.