Systemic T Cell Subsets and Cytokines in Patients With Homozygous Sickle Cell Disease and Asymptomatic Urinary Tract Infections in Togo.

In sickle cell disease (SCD), cytokine expression influences the pivotal pathways that contribute to disease pathogenesis. Additional infection could affect the immune profile of patients with SCD and increase disease mortality. The aim of this study was to investigate the cytokines and T helper cells profile in patients with asymptomatic urinary tract infection and homozygous SCD (HbSS).

[Anemia in blood donors and criteria of hemoglobin level control at the national blood transfusion center (NBTC) of Lomé, Togo].

Introduction: The aim of this study was to evaluate the prevalence of anemia among blood donors at Lomé national blood transfusion center (NBTC) and to identify criteria for controlling hemoglobin level in blood donation candidates.

Methods: We determined the hemoglobin level using HemoCue® 201+. To identify the hemoglobin level control criteria, the judgment parameters were the proportion of anemic donors based on the number of blood donations in the last 12 months and the staining of the conjunctiva.

[Characteristics of chronic lymphocytic leukemia in Togo].

The epidemiological, clinical and biological characteristics of chronic lymphocytic leukemia (CLL) are little studied in Togo. The purpose of this study was to describe these characteristics at the time of diagnosis. We conducted a retrospective and descriptive study of patients diagnosed at the University Hospital Campus from January 1999 to December 2018.

[Quality control of red blood cell pockets produced at Centre National de Transfusion Sanguine de Lomé].

Introduction: at the National Center for Blood Transfusion (NCBT) in Lomé, whole blood is systematically separated into its various labile blood products. This study aims to assess the quality of the red blood cell concentrates (RBCC) produced.

Methods: we conducted a cross-sectional study on 260 RBCCs (204 adult units and 56 paediatric units) from January to March 2018.

Intrauterine Growth Retardation Complicated by Biermer's Disease: An Observation in Togo.

Objective: To report the first case in Togo of Biermer's disease associated with intrauterine growth retardation (IUGR) in a 39-year-old pregnant woman.

Observation: The patient with phenotype AA, born on 20/02/1978, GP (a spontaneous abortion at 3 months), was referred to hematology on 17 March 2017 for anemia at 26 weeks of amenorrhea (WA). She had received martial treatment with ferrous fumarate 66 milligrams daily.