Publications by authors named "E P Vovenko"

Using a fine-tip oxygen microelectrodes the longitudinal gradients of oxygen tension (pO2) have been studied in small arterioles (with lumen diameter in control of 5 +/- 20 microm) and in capillaries of the rat brain cortex during stepwise decrease of the blood haemoglobin concentration [Hb] from control [Hb]--14.4 +/- 0.3 g/dl to 10.

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Acute anemia (stages 1 and 2) led to decreases in pO2 at the walls of radial venules (lumen diameter 13.1 +/- 0.5 microm) and in the tissues at distances of up to 40 mum from the walls, indicating increased extraction of oxygen from the blood by the smallest microvessels.

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Acute anemia was shown to result in increase of pO2 in the wall of radial arterioles (with lumen diameter of 14.7 +/- 0.9 microm) and in the tissue near the studied arterioles, while decreasing as compared to control values at the distance 60 urn from the vessel wall.

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Modified needle oxygen microelectrodes and vital microscopy were used to measure transmural oxygen tension gradients (PO2) in pial arterioles with lumen diameters of 20-90 microm. A relationship between the magnitude of the transmural PO2 gradient and arteriole wall tone was found: in control conditions, PO2 gradients were 1.17 +/- 0.

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Using modified oxygen needle microelectrodes, vital microscopy with video-recording facilities, measurements of tissue oxygen tension (PO2) profiles near the cortical arterioles and transmural PO2 gradients on pial arterioles of the rat were performed. At control transmural PO2 gradient averaged 1.17 +/- 0.

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