Structure and signaling at hydroid polyp-stolon junctions, revisited.

The gastrovascular system of colonial hydroids is central to homeostasis, yet its functional biology remains poorly understood. A probe (2',7'-dichlorodihydrofluorescein diacetate) for reactive oxygen species (ROS) identified fluorescent objects at polyp-stolon junctions that emit high levels of ROS. A nuclear probe (Hoechst 33342) does not co-localize with these objects, while a mitochondrial probe (rhodamine 123) does.

[Correlation of the spermatozoa morphological anomaly with the presence of aneuploidies in its nuclei in the patients with astheno-, oligo- and teratozoospermia].

Examination of the numerous anomalies of the chromosomes 13, 18, 21, X, Y was carried out using FISH method before the IVF attempt in the patients with astheno-, oligo- and teratozoospermia. The percentage of aneuploid spermatozoa was magnificently higher (p < 0.05) in patients with oligozoospermia comparing with the ones with astheno- and teratozoospermia.

[Effect of the treatment of relapsing bronchitis in children with combined interferon preparations applicated by different methods].

The clinico-immunological effect and significance of the rectal and inhalation methods of the application of recombinant IFN-alpha2 with complex immunoglobulin preparation (CIP) in the treatment of relapsing bronchitis in children have been determined. The determination of the levels of interferon activity in buccal secretions and in venous blood permits the objective evaluation of the immune responsiveness of the body and the treatment effect. The immunocorrecting action of the combined immunobiological preparation (recombinant IFN-alpha2 and CIP) is manifested by an increased level of endogenic interferon and the stimulation of phagocytic activity.

[The pathogenetic role of the infection component in children with lymphadenopathy under modern conditions].

Apart from lymphadenopathy types observed in well-known diseases (oncology and hematology pathologies, systemic lesions of connective tissues, tuberculosis, brucellosis, infection mononucleosis, toxoplasmosis, AIDS and other specific processes), there is an extensive group of lymphadenopathy (up to 70% of all disease cases), whose cause cannot be diagnosed by using the routine examination schemes. This was reflected in the diagnosis of "lymphadenopathy of unverified etiology" according to the MKB-1 now in force. Investigations of the role (in etiopathogenesis) of unverified lymphadenopathy types as observed in children with the infection component as well as optimization of their diagnosis and treatment schemes are elucidated in the paper.

Chronobiological aspects of melatonin-produced antioxidant effects in senescent rats.

Melatonin in low doses of (0.05 and 0.5 mg/kg) administered to senescent rats in winter and summer inhibited free radical oxidation and LPO.