Publications by authors named "E P Cook"

Objectives: Given the rapid growth of the field of health policy and systems research (HPSR), it is important to monitor the research environment, especially the evolution of HPSR research outputs in low- and middle-income countries (LMICs). The objective of this study was to generate quantitative metrics to assess the production of HPSR publications and the role of the Alliance for Health Policy and Systems Research (the Alliance) grant-funded projects in 11 LMICs over the past 20 years.

Methods: We conducted a systematic literature search for HPSR literature from 1999 to 2020 pertaining to 11 target LMIC countries, including grey literature.

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The Engraft Learning Health Network (LHN) aims to improve outcomes for patients undergoing transplant and cellular therapy (TCT) through a collaborative, data-driven approach. Engraft brings together diverse stakeholders, including clinicians, patients, caregivers, and institutions, to standardize best practices and accelerate the dissemination of innovations in TCT care. By establishing a multicenter, real-world clinical registry focused on rapid-cycle quality improvement (QI) and implementation research, Engraft seeks to reduce variability in clinical practice to improve TCT outcomes across centers.

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Military bases and airports are often contaminated by per- and polyfluoroalkyl substances (PFAS) due to the repeated use of aqueous film forming foams (AFFFs) from decades of training exercises, equipment testing, and extinguishing of fuel- and solvent-based fires. Pump-and-treat systems combined with sorption processes are common ex situ remediation strategies; however, they can be expensive and may require decades of operation, particularly at sites where long-term diffusion and desorption of contaminants are the primary release processes. Alternatively, in situ chemical oxidation is an effective remediation strategy in which oxidants (e.

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Article Synopsis
  • Recurrent hyperkalemia (HK) in patients with chronic kidney disease (CKD) is linked to significantly higher risks of all-cause mortality and cardiovascular (CV) issues compared to patients with normal potassium levels.
  • The study involved matching 6,337 patients with recurrent HK to those with normokalemia, adjusting for relevant factors, to ensure a fair comparison.
  • Findings indicated that recurrent HK is particularly detrimental, increasing risks for major adverse cardiovascular events (MACE+) and hospitalizations due to arrhythmias, affecting both the overall CKD population and those with co-occurring heart failure.
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Peri-urban environments, characterized by dense human populations, cohabiting livestock, and complex food systems, serve as hotspots for food contamination and infectious diseases. Children aged 6-24 months are particularly vulnerable as they often encounter contaminated food and water, increasing their risk of food-borne disease, with diarrhea being a common symptom. We investigated the prevalence of antimicrobial resistance (AMR) in pathogenic Escherichia coli from 6-24 months-old children, their food, and cohabiting livestock, in Dagoretti South subcounty in Nairobi, Kenya.

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