[Change in the ratio of blood saturated to unsaturated fatty acids is a universal marker of lipid metabolic disorder in patients with cholelithiasis].

Aim: To study the spectrum of serum fatty acids (SSFA) and the composition of blood lipids in cholelithiasis (CL) in various ethnic groups of East Siberia.

Subjects And Methods: A clinical and epidemiological study was conducted, during which ultrasonography and oral cholecystography were used to examine 991 Khakases and 934 Europoids in Khakassia and 652 Evenks and 996 Europoids in Evenkia. Biochemical tests were performed to determine serum lipids in 20% of the random sample.

[Efficacy of Kolofort for the treatment of patients with irritable bowel syndrome].

Aim: to determine the efficacy and safety of Kolofort in the treatment of patients with irritable bowel syndrome (IBS).

Subjects And Methods: 52 patients (16 men and 36 women) aged 26 to 59 years were examined over 4 months to rule out organic disease. The diagnosis of IBS was established on the basis of the Rome III diagnostic criteria (2006).

Peptic Ulcer Disease and Helicobacter pylori Infection in Different Siberian Ethnicities.

Background: The high prevalence of Helicobacter pylori (H. pylori) infection in eastern Siberia is consistently established. In the same geographic area, however, fragmentary information is available on the epidemiology of the peptic ulcer disease (PUD).

[Peculiarities of relationship between atrophic gastritis and stomach cancer in the population of Eastern Siberia].

The authors studied the prevalence of atrophic gastritis, H.pylori strains carrying the CagA gene, seeding and apoptosis indices of gastric mucosa in indigenous and newcomer residents of Evenkia. A total of 136 Evenks and 159 newcomers were examined using fibrogastroscopy and biopsy of antral gastric mucosa.

[Serum fatty acid and lipid spectrum in patients with cholelithiasis].

Caucasoids and mongoloids from different regions of Siberia were examined for the prevalence of cholelithiasis, serum lipid and fatty acid profiles. In Caucasoids, unlike Mongoloids, cholelithiasis was associated with increased serum cholesterol. This finding suggests that relative stability of lipid metabolism in Mongoloids protects them from biliary pathology.