Publications by authors named "E P Bosmans"
Article Synopsis
- The study investigates the short- and long-term impacts of SARS-CoV-2 on sperm quality, revealing a lack of established knowledge due to insufficient longitudinal research.
- Evaluating sperm parameters included assessments like motility, morphology, DNA damage, and the presence of anti-sperm antibodies, which classified patients based on their antibody response post-infection.
- Findings indicate that SARS-CoV-2 affects various sperm quality metrics, with most changes being temporal and suggesting that individual immune response levels influence recovery to baseline sperm quality after infection.
Article Synopsis
- The study investigates whether a simplified IVF culture system (SCS) can produce similar pregnancy outcomes compared to the more traditional intracytoplasmic sperm injection (ICSI) method.
- During the research, 653 cycles using both methods were analyzed, finding that while fertilization rates favored SCS, ongoing pregnancy rates were comparable and did not show significant differences.
- Results indicated that the SCS was as effective as ICSI in terms of ongoing pregnancy, miscarriage, and implantation rates, suggesting that SCS could be a viable alternative for selected patients.
Research Question: Is there a difference in perinatal outcome in the same patient cohort for babies conceived following randomization of sibling oocytes allocated to a simplified IVF culture system (SCS) or intracytoplasmic sperm injection (ICSI) followed by conventional culturing?
Design: The study compared the perinatal outcomes of 367 babies born from 1 January 2013 until 31 December 2020 after using split SCS and ICSI insemination of sibling oocytes in a selected group of normo-responsive women, excluding cases of severe male infertility. Primary outcome measures were preterm birth (PTB; <37 weeks' gestation), low birthweight (LBW; <2.5 kg) and small for gestational age (SGA) as a primary outcome parameter while secondary outcome measures included mean birthweight, mean gestational age, extreme prematurity (<32 weeks), very low birthweight (<1.
Objective: To study the contagiousness of sperm and its influence on fertility after recovery from COVID-19 infection.
Design: Prospective cohort study.
Setting: University medical center.
Article Synopsis
- The study aimed to establish a sperm DNA fragmentation index (DFI) cutoff of 26% associated with clinical pregnancies during intra-uterine insemination (IUI) and evaluate the impact of Human Papillomavirus (HPV) on sperm DNA damage.
- In a multi-center study with 161 infertile couples undergoing 209 IUI cycles, results showed that couples with a male DFI above 26% experienced significantly lower clinical pregnancy rates compared to those below this threshold (OR 0.0326).
- HPV was present in 14.8% of sperm samples and was linked to higher DFI levels (29.8% vs. 20.9% for HPV