Publications by authors named "E Ozyar"
Objective: Intracranial hemangiopericytomas (HPC) are rare tumors. Radiotherapy (RT) is frequently performed after surgery, depending on tumor size, location, and the type of resection. Moreover, RT is preferred as an effective treatment for local recurrence and metastasis.
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- - Stereotactic body radiotherapy (SBRT) is a key method for treating lung tumors but faces challenges like anatomical changes during treatment; magnetic resonance-guided online adaptive SBRT (MRgSBRT) offers a solution for improving safety and outcomes.
- - A study analyzed 64 patients with lung tumors treated using MRgSBRT, showing high local progression-free survival rates of 96.3% at one year and 86.4% at three years, with no local recurrences in patients receiving higher doses.
- - The results support MRgSBRT's effectiveness in treating lung lesions without significant toxicity, indicating the need for further prospective studies to validate these findings.
Purpose: The purpose of this multicenter retrospective study was to analyze the clinical and radiological effects of bevacizumab (BV) on radionecrosis (RN) that developed after stereotactic radiotherapy (SRT) for brain metastasis.
Methods: Forty patients with SRT related symptomatic brain RN treated in 10 radiation oncology centers were analyzed. The clinical response to BV treatment was categorized as follows: complete (no additional treatment required), partial (requiring either steroids or repeat BV), and unresponsive (requiring surgery).
Article Synopsis
- Locally recurrent nasopharyngeal carcinoma (NPC) poses significant treatment challenges due to the absence of standardized guidelines for postoperative re-irradiation (re-RT).
- This article reviews international recommendations for managing resectable cases of locally recurrent NPC, focusing on re-RT strategies and addressing controversial issues like surgical margins and resectability criteria.
- The consensus suggests a clearer definition of resectability, optimal re-RT doses around 60 Gy, and emphasizes the potential benefits of hyperfractionation to minimize treatment toxicity, aiming to improve patient outcomes.
Nuclear protein in testis (NUT) carcinoma is a rare neoplasm arising mainly from midline structures. It is an aggressive type of carcinoma associated with poor survival despite the use of multiple treatment modalities. Here, we present a case of a 17-year-old paediatric patient with NUT carcinoma of larynx, which is even rarer among all reported cases.
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