Publications by authors named "E Ouattara"
Since the 60s, and particularly after various scandals in the 90s, national research ethics committees in Africa have established themselves as key players in the field of international clinical research. Notably based on the principle of double ethical review, their existence has historically been aimed at preventing a form of ethical dumping, a temptation that still exists today on the part of some research promoters. While the international framework of “soft” law has favored their emergence and legitimacy, a legal and regulatory framework of “hard” law is also necessary at local level for each national research ethics committee, to ensure its proper functioning and the optimal fulfillment of its missions.
View Article and Find Full Text PDFBackground: Since 2021, 3 variants of concern (VOC) have spread to France, causing successive epidemic waves.
Objectives: To describe the features of Alpha, Delta and Omicron VOC circulation in the Nouvelle-Aquitaine region, France, between February 2021 and February 2022.
Study Design: Data from the three university hospitals (UH) of Nouvelle-Aquitaine were used to describe regional SARS-CoV-2 circulation (RT-PCR positive rates and identified VOC) as well as its consequences (total number of hospitalizations and admissions in intensive care unit).
Introduction: Even though France was severely hit by the COVID-19 pandemic, few studies have addressed the dynamics of the first wave on an exhaustive, nationwide basis. We aimed to describe the geographic and temporal distribution of COVID-19 hospitalisations and in-hospital mortality in France during the first epidemic wave, from January to June 2020.
Methods: This retrospective cohort study used the French national database for all acute care hospital admissions (PMSI).
Article Synopsis
- * Of the 7,485 pediatric COVID-19 cases studied, 26.6% (1,988 patients) were admitted to critical care units, with younger age, pediatric multisystem inflammatory syndrome (PIMS), respiratory issues, and underlying conditions being significant risk factors.
- * The rate of critical care admissions decreased over the pandemic waves, with a total of 32 deaths (0.4%) and a median age of 6 years among those who died, highlighting specific age groups, especially newborn
Article Synopsis
- A study was conducted in two nursing homes in southwestern France to investigate COVID-19 breakthrough infections among residents who were mostly vaccinated, during active COVID-19 clusters in early 2021.
- Out of 152 residents, 31% had confirmed COVID-19 infections, including those who were fully vaccinated, with some experiencing severe illness and one fatality.
- The study found that infected residents had significantly higher antibody levels compared to non-infected vaccinated residents, suggesting that additional vaccine doses may be beneficial for this vulnerable population.