Publications by authors named "E Otsuji"
No established method currently exists for evaluating tumor-infiltrating lymphocytes (TILs) in gastric cancer (GC), and their clinical significance based on infiltration site in GC remains unclear. In this study, we developed a method to evaluate TILs according to their infiltration site as a prognostic marker for GC. We retrospectively analyzed 103 patients with advanced GC who underwent curative resection.
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- A study explored the potential for shorter oxaliplatin adjuvant chemotherapy for patients with high-risk stage II and low-risk stage III colon cancer, analyzing recurrence risks in 396 surgical patients.
- The findings showed that patients in the low-risk group had a better 3-year relapse-free survival rate, but those with high preoperative serum carcinoembryonic antigen (CEA) levels who didn't complete their treatment had poorer outcomes.
- The study concluded that patients in the low-risk group with elevated CEA levels should not reduce their chemotherapy duration, as it negatively affects their prognosis.
Background: Postoperative neurogenic bladder (PONB) frequently occurs as a complication after rectal cancer surgery. This study aimed to analyze risk factors for developing PONB after rectal cancer surgery, particularly the association between pelvic anatomy and visceral fat mass.
Methods: We included 138 patients who underwent rectal resection for lower rectal cancer in our department between 2017 and 2021.
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- The glycocalyx (GCX) is a cellular surface layer linked to cancer, specifically its growth and spread, with glypican-1 (GPC1) being a key protein in this process for esophageal squamous cell carcinoma (ESCC).
- A study measured GPC1 levels in the plasma of advanced esophageal cancer patients and found high GPC1 levels correlated with worse clinical outcomes and significant cancer characteristics, such as tumor size and metastasis.
- The findings suggest that extracellular GPC1 can be a less invasive biomarker for monitoring ESCC progression and might serve as a potential target for new treatments.
The anatomical dimensions and the shape of the pelvis influence surgical difficulty for rectal cancer. Compared to conventional laparoscopic surgery, robot-assisted surgery is expected to improve surgical outcomes due to the multi-joint movement of its surgical instruments. The aim of this study was to investigate the impact of pelvic anatomical indicators on short-term outcomes of patients with rectal cancer.
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