Publications by authors named "E Orsenigo"
Objectives: The aim of this retrospective study is to assess the incidence of morbidity and mortality related to cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) and to evaluate their predictors, in patients with peritoneal metastasis of ovarian origin.
Methods: A retrospective multicenter study was carried out investigating results from eight Italian institutions. A total of 276 patients met inclusion criteria.
Despite the recent introduction of mold-active antifungal prophylaxis (MAP), breakthrough invasive fungal infections (b-IFI) still represent a possible complication and a cause of morbidity and mortality in hematological patients and allogeneic hematopoietic stem-cell transplantation recipients (HSCT). Data on incidence and type of b-IFI are limited, although they are mainly caused by non- and non- molds and seem to depend on specific antifungal prophylaxis and patients' characteristics. Herein, we described the clinical presentation and management of two cases of rare b-IFI which recently occurred at our institution in patients undergoing HSCT and receiving MAP.
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- Acute appendicitis (AA) is a frequent cause of abdominal pain that may require surgery and can lead to serious complications in about 20% of cases, complicating diagnosis and treatment.
- A recent consensus statement by experts focused on the latest evidence and best practices for diagnosing and treating AA, taking into account various medical sources and established guidelines.
- Key symptoms include fever and migratory pain, with diagnostic tools such as laboratory tests and imaging being essential; surgery is advised for complicated cases, while laparoscopic surgery is recommended and antibiotics post-surgery are reserved for complicated AA only.
The aim of this study is to assess the morbidity and mortality related to cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with colo-rectal carcinomatosis. A retrospective multi-institutional study from seven Italian Centers was performed. One hundred and seventy-two patients, submitted to cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) to treat carcinomatosis of colorectal origin, were recorded.
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