Publications by authors named "E Onalan"
Article Synopsis
- - This study compares chronic immobilization stress (CIS) and cisplatin treatments as models for studying premature ovarian failure (POF) in rats, focusing on their effects on ovarian function and the potential benefits of a mitochondrial protective agent (AP39).
- - Sixty female rats were divided into six groups to assess different treatment combinations and evaluate factors like hormonal levels, estrous cycles, and ovarian health through various tests and observations.
- - The results showed that both CIS and cisplatin treatments led to significant declines in ovarian health markers, and AP39 did not fully return these parameters to normal, suggesting that the CIS model may better represent stress-induced ovarian dysfunction rather than typical POF.
Article Synopsis
- The study explored the protective effects of humanin (HN) on myocardial injury caused by myocardial infarction (MI) in rats, focusing on its interaction with the Notch signaling pathway.
- Rats were divided into groups to receive varying treatments of HN and MI, allowing researchers to analyze the expression levels of Notch signaling components and other cardiac injury markers.
- Results indicated that HN administration before MI significantly increased the levels of Notch signaling proteins and reduced indicators of cardiac damage, suggesting that HN could serve as a cardioprotective agent.
Background: To investigate the mechanism of action of stathmin1 (STMN1) in mesothelioma (MSM) and whether it has any role in its treatment.
Methods: STMN1 expression was examined using immunohistochemistry in biopsy tissues taken from MSM patients. The relationships between the levels of STMN1 expression in the pathology preparations of MSM patients, and the clinicopathological characteristics of these patients, and their survival times were investigated.
Attitude towards seeking psychological help regarding psychiatric symptoms and stigma in patients with fibromyalgia.
Eur Rev Med Pharmacol Sci
November 2023
Objective: The current study aimed to examine the psychiatric symptoms that can be seen in fibromyalgia (FM) patients, their attitudes toward seeking psychological help, and their concerns about stigma. Besides, it was investigated whether the stigma concerns that they may experience about receiving psychiatric treatment constitute an obstacle for patients to receive psychiatric treatment.
Subjects And Methods: This cross-sectional descriptive study was conducted between February and July 2020.
Background: Mutual regulation between immune system and gut microbiota is achieved through several mechanisms including the engagement of toll-like receptors (TLRs) which is expressed on numerous cell types. In this study we aimed to explore the association between food allergies and TLR gene polymorphisms in association with gut microbiota.
Methods: Toll-like receptors polymorphism frequencies and some bacteria in the gut microbiota in 130 infants aged 1-24 months with egg and/or milk allergy in a prospective cohort were compared with 110 non-food allergic controls.