[Correction of oxidative stress in the experimental thermal burn of the skin].

The white breedless rats have been investigated in conditional reflex activity restoration dynamics, exercise tolerance and prominence of oxidative stress after local burn injury of skin and effectiveness of Plaferon use, administered in the first three days after burn injury modeling. One day before administration the background values and the following dynamics of indexes on the first, third and fifth days were recorded. Tolerance exercise has been much higher in the group of animals receiving the Plafreon during the whole period of observation, but the prominence of oxidative stress has been lower than in the group of animals receiving no treatment.

[Influence of the plaferon on healing of burned wounds of III - IV degrees].

The purpose of the given work was studying influence of a preparation Plaferon on the process of healing burned wounds. Experiments was carried out on 30 rats Wistar (the mass of body 220-250 g), that was divided into 3 groups: 1st group (control) -burns without treatment, 2nd group - treatment only with Dermazin, 3rd group - treatment with Dermazin and Plaferon. As a result of the burn wound modeling, it is established that under the effect of the thermal interaction the rats of all experimental groups had severe burns of the skin of III degree.