Publications by authors named "E O Saksonova"

Aim: To evaluate the role of botulinum toxin type A in the acute phase of facial nerve injury after neurosurgical surgery.

Materials And Methods: The study involved 55 patients with acute facial muscle paresis caused by facial nerve injury during surgery on the posterior cranial fossa and cerebello-pontine angle (CPA). The first group consisted of 35 patients (mean age, 48.

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A clinical and electrophysiological (EMG, ENMG, the blink reflex) examination has been carried out in 85 patients with facial nerve lesions of different etiology. A control group included 25 healthy people. Two schemes of botulinum toxin type A (lantox) injections into hyperactive facial muscles have been elaborated.

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Parameters of lipid peroxidation (LP) and antioxidant activity (AOA) of tear and blood plasma were examined in 22 healthy subjects (44 eyes) as well as in 33 patients with peripheral vitreochoreoretinal dystrophies (PVCRD--60 eyes), in 32 patients with non-operated dystrophic retinal detachment (DRD--34 eyes) and in 135 patients with operated retinal detachment, stable visual functions and with the postoperative period ranging from 4 months to 10 years (137 eyes). The results denoted a lower tear AOA (on the average by 35%) in patients with DRD and PVCRD, whereas, the blood plasma AOA or LP products' content remained unchanged. It is indicative of a local nature of metabolic impairments, specifically, of impairments in the system of antioxidant protection of the eye.

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A method for surgical treatment of grave detachment of the retina with multiple, giant, and postequatorial ruptures has been developed. The method consists in combined extrascleral filling making use of bichannel silicon explants. A total of 78 patients (78 eyes) were operated on.

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