Publications by authors named "E O Hanlon"

Background: Individuals with posttraumatic stress disorder (PTSD) have high rates of cardiovascular disease (CVD) and increased cardiometabolic CVD risk factors (CVDRFs, e.g., hypertension, hyperlipidemia, or diabetes mellitus).

View Article and Find Full Text PDF

We previously demonstrated that near-infrared spectroscopy in vivo presents spectral features at 895 and 861 nm that accurately classify Alzheimer's disease, mild cognitive impairment, and age-matched control subjects. Our purpose here is to associate the 895 nm signal with [Formula: see text]-amyloid. We applied our feature selection technique to subjects with and without leptomeningeal amyloid.

View Article and Find Full Text PDF
Article Synopsis
  • The review examines how the endocannabinoid system (ECS) affects energy balance and metabolism, highlighting its role in obesity and related disorders.
  • Recent studies reveal the ECS's influence on food intake, fat storage, and insulin sensitivity, while also exploring its interactions with gut microbiota and genetic factors.
  • Although past ECS-targeting treatments faced challenges, new peripherally restricted CB1 antagonists may offer safer options for managing obesity, paving the way for future research and therapeutic strategies.*
View Article and Find Full Text PDF

The existence of life-history trade-offs is a fundamental assumption of evolutionary biology and behavioural ecology, yet empirical studies have found mixed evidence for this. Such trade-offs are expected when individuals vary in how they allocate their limited resource budgets between different life-history functions (variation in resource allocation), but they may be masked when individuals vary in how many resources they have acquired that they can later allocate to life-history functions (variation in resource acquisition). We currently lack studies on the extent to which individual differences in behaviour reflect variation between individuals in resource acquisition and resource allocation.

View Article and Find Full Text PDF

Hypertension is ubiquitous among older adults and leads to major adverse cardiovascular events. Nonpharmacologic lifestyle interventions represent important preventive and adjunct strategies in the treatment of hypertension and have benefits beyond cardiovascular disease in this population characterized by a high prevalence of frailty and comorbid conditions. In this review, the authors examine nonpharmacologic interventions with the strongest evidence to prevent cardiovascular disease with an emphasis on the older adults.

View Article and Find Full Text PDF