Cross-Cultural Validation of the Binge Eating Disorder Screener-7 (BEDS-7) Across 42 Countries.

Objective: This study aimed to evaluate the reliability and validity of the Binge Eating Disorder Screener-7 (BEDS-7) across 42 countries and 26 languages, assessing its reliability and validity as a screening tool for binge-eating disorder (BED) in diverse cultural contexts. Specifically, it sought to enhance early recognition of BED symptoms in primary care settings globally, contributing to a standardized framework for assessing BED.

Method: The International Sex Survey, a cross-sectional online study, was conducted in 42 countries and 26 languages.

Differential emotional responses to positive and negative visual perception in children and young adults: An electroencephalography study.

Currently, the number of children with problems associated with mood disorders and emotion regulation is increasing. However, little is known about the development of emotional responses, especially in the developmental population. To examine the temporal dynamics of emotional neuronal activation, we presented a subset of standardized emotional pictures from the International Affective Picture System dataset to 45 children and young adult participants.

An Examination of Visitor and Tiger Activity Between Two Zoo Tiger Groups.

Sumatran tigers (Panthera tigris sumatrae) are currently listed as critically endangered on the IUCN Red List. In modern zoos, the need to balance the welfare of tigers while maintaining visitor interest presents a significant challenge. The aim of this study was to assess the behaviour of five Sumatran tigers housed in two separate groups and habitat areas (male housed alone; female with three cubs), as well as in relation to visitor crowd size and sound intensity (dB) near the habitats.

Proteomic analysis reveals candidate molecules to mediate cortical pathology and identify possible biomarkers in an animal model of multiple sclerosis.

Introduction: Multiple Sclerosis (MS) is a complex neurodegenerative disease marked by recurring inflammatory episodes, demyelination, axonal damage, and subsequent loss of function. MS presents a wide range of clinical courses, with the progressive forms leading to irreversible neurological disability. Cortical demyelinating lesions are central to the pathology of these progressive forms, gaining critical importance in recent decades due to their strong correlation with physical disability and cognitive decline.

Mucin 4 expression is associated with metastasis in triple-negative breast cancer and can be tackled by soluble TNF blockade, improving immunotherapy outcome.

Purpose: Triple-negative breast cancer (TNBC) has the worst prognosis among breast cancers. Immunotherapy is a therapeutic option, but there is no biomarker to guide promising combination treatments. Mucin 4 (MUC4) favors metastasis in preclinical cancer models.