Objectives: The study evaluated sub-microscopic malaria infections in pregnancy using two malaria Rapid Diagnostic Tests (mRDTs), microscopy and RT-PCR and characterized Plasmodium falciparum dihydrofolate reductase (Pfdhfr) and Plasmodium falciparum dihydropteroate synthase (Pfdhps) drug resistant markers in positive samples.
Methods: This was a cross sectional survey of 121 pregnant women. Participants were finger pricked, blood drops were collected for rapid diagnosis with P.
Background: There have been suggestions that hematologic abnormalities in COVID-19 are linked with the progression and severity of diseases and mortality. Lymphopenia, sepsis, and thrombocytopenia were highly reported in patients with COVID-19. This study investigated the significance of hematologic abnormalities in patients with COVID-19 in Lagos, Nigeria, and its potential as a diagnostic tool for COVID-19 severity.
View Article and Find Full Text PDFThe objective of this study was to assess the factors affecting testing behaviours amongst the population in Ondo and Lagos States. A cross-sectional study involving 704 individuals who were considered eligible for COVID-19 testing in 4 local governments in Lagos (307) and Ondo (397) states in Nigeria, was conducted from April-June 2021. Respondents were selected using simple random sampling.
View Article and Find Full Text PDFBackground: A common complication of any respiratory disease by a virus could be a secondary bacterial infection, which is known to cause an increase in severity. It is, however, not clear whether the presence of some opportunistic pathogens called pathobionts contributes to the severity of the disease. In COVID-19 patients, undetected bacterial co-infections may be associated with the severity of the disease.
View Article and Find Full Text PDFBackground: Paediatric endocrinology is a nascent subspecialty in Nigeria.Previous reports suggest a poor awareness of paediatric endocrine disorders resulting in late presentation, missed diagnosis and unnecessary death.
Objectives: The study aims to report the prevalence of paediatric endocrine disorders at UNIOSUN Teaching Hospital (UTH) and to provide essential information to enhance early presentation and management.