Objective: To determine if the number of vaso-occlusive events in SCD relates to plasma concentration of fucosyltransferase 7 (FUT7), which catalyses the synthesis of selectin ligands.
Design: A prospective, analytical study.
Setting: Haematology and Chemical Pathology Departments of tertiary healthcare centres.
Background: Single-donor platelet transfusion is the preferred therapeutic option for patients with platelet insufficiency and its effectiveness is partly dependent on the yield.
Aim: To determine the platelet yield and predictors of platelet yield in single-donor apheresis.
Materials And Methods: This was a five-year review of the data on single-donor apheresis using the Haemonetics Apheresis machine MCS+ at Alex Ekwueme Federal University Teaching Hospital Abakaliki Ebonyi state.