Toxicity, Antibacterial, and Phytochemical Analyses of Pierre Extracts.

Medicinal plants are traditionally used in Gabon to treat several types of illnesses. The study's purpose was to determine the toxic, antibacterial, and anti-inflammatory effects of Pierre extracts and to characterize their phytochemical compounds. Toxicity was evaluated on frog tadpoles ( Hallowell).

Profile of loiasis infection through clinical and laboratory diagnostics: the importance of biomarkers.

Background: Detection of Loa loa microfilariae in peripheral blood is insensitive given only 30% of individuals are microfilaraemic while 70% are amicrofilaraemic with a variety of clinical signs. Biomarkers may improve the diagnosis of loiasis.

Methods: A total of 545 individuals exposed to L.

The Human Filaria : Update on Diagnostics and Immune Response.

loiasis was considered an anecdotal disease 30 years ago. Its spread in Equatorial Africa and the side effects associated with mass drug administration programs against filariasis in co-endemic areas have drawn the attention of the international research community. Progress in research conducted to date has provided insight into the immunobiology of this parasite.

In vitro activities of plant extracts on human Loa loa isolates and cytotoxicity for eukaryotic cells.

Loa loa, a filarial worm, can cause fatal encephalitis in humans. In an attempt to find alternatives to the standard treatments (ivermectin and diethylcarbamazine citrate), we tested 12 methanolic extracts of nine traditional plant remedies. The extracts (100-0.