[Phenomenon of increased resistance of yeast-like fungi to nystatin].

The results are presented of in vitro investigations of the sensitivity of 225 strains of yeast-like fungi to nystatin. The strains were isolated from cutaneous and mucosal lesions. In the study nystatin concentration 10 micrograms/ml of the substrate was used and a two-grade scale of evaluation was applied: sensitive or resistant to the drug.

[Antifungal activity of itraconazole and ketoconazole investigated in vitro, determined with minimal inhibitory concentrations and mycelial cell transformation in Candida albicans].

Results of studies "in vitro" of the susceptibility of 82 strains of Candida albicans for itraconazole and ketoconazole have been report. The strains were isolated from lesions of the mucous membranes and skin. The susceptibility of Candida albicans was tested to Minimal Inhibitory Concentration (MIC) and Total Inhibition Germination Tubes (TI100).

[Comparison of the susceptibility of Candida strains to ketoconazole and itraconazole in in vitro experiments].

The activity of ketoconazole and itraconazole against 102 strains of Candida sp. was compared in the investigation "in vitro". The investigational material was taken from patients with different types of mycosis.

[Effect of itraconazole on the process of mycelial transformation of Candida albicans cells in human serum].

Results of in vitro studies on the influence of itraconazole on mycelial transformation of 88 Candida albicans strains are presented. The drug influenced a number of cells capable to produce filaments. The number of those cells diminished gradually together with the increase of the drug concentration.

[In vitro investigations of Candida strains for itraconazole].

Results of studies in vitro of the susceptibility of 102 strains of Candida type (88--Candida albicans, 7--Candida intermedia, 3--Candida parapsilosis, 1--Candida stellatoidea, 3--Torulopsis candida), to itraconazole have been reported. The strains were isolated from lesions of the skin and mucous membranes. The strains tested showed no resistance to this drug.