Publications by authors named "E Nickel"
Background: The past decade has witnessed a surge in the development of artificial intelligence (AI)-based technology systems for healthcare. Launched in November 2022, ChatGPT (Generative Pre-trained Transformer), an AI-based Chatbot, is being utilized in nursing education, research and practice. However, little is known about its pattern of usage, which prompted this study.
View Article and Find Full Text PDFProblem: Trust is central to the development of nurse-patient relationships. Pediatric nurses encounter difficulties developing trust with children and their caregivers. The purpose of this scoping review was to identify, examine, and summarize available evidence on the concept of trust among nurses and children/caregivers when admitted to hospital inpatient care units.
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- Tolerance to a substance requires increasing amounts of it over time to achieve the same effects, but the mechanisms behind this process are not fully understood.
- Researchers are using Drosophila melanogaster (fruit flies) to study tolerance, as they share genetic similarities with humans that are relevant to alcohol responses and disorders.
- The study reveals an inverse relationship between initial resistance to ethanol and tolerance development, suggesting that some mutants may display 'secondary' tolerance due to their initial sensitivity, and it proposes a new method for evaluating tolerance that takes this relationship into account.
Article Synopsis
- In the early days of anaesthesia, the fasting period for liquids was short, but by the mid-20th century, a 'nil by mouth after midnight' rule became standard for all patients.
- Over time, anaesthesiology bodies recognized that clear liquids empty quickly from the stomach and adjusted recommendations to allow drinking them up to 2 hours before surgery, with no evidence showing it increases aspiration risk.
- Despite these advancements, patients often still fast for an average of 12 hours due to hospital practices, leading some facilities to permit clear liquids within 2 hours of anaesthesia, warranting further research on safety and risks.
Article Synopsis
- Tolerance requires increased substance amounts after initial exposure to achieve the same effects.
- Researchers have studied model organisms, like fruit flies, to understand tolerance due to their relevance to human alcohol responses and overlapping genetic factors.
- This study reveals an inverse relationship between initial resistance to alcohol and tolerance, suggesting that measuring tolerance should focus on relative change in sedation time, and offers a method to evaluate potential tolerance mutants using linear regression analysis.