Publications by authors named "E Navarro-Gonzalez"
Papillary thyroid carcinoma (PTC) is the most common histological category of thyroid cancer. In recent years, there has been an increasing number of studies on lncRNAs in PTC. Long intergenic non-protein coding RNA 887 (LINC00887) is a critical oncogene in developing other cancers.
View Article and Find Full Text PDFObjective: The aim of this study is to describe the characteristics, survival and prognostic factors of a cohort of patients with bone metastases (BMs) from differentiated thyroid carcinoma (DTC).
Methods: This was a multicenter retrospective observational study including patients diagnosed with BMs from DTC between 1980 and 2021. A Cox regression was performed to study prognostic factors for 5- and 10-year survival.
Article Synopsis
- Thyroid carcinoma (TC) includes two main types: medullary (MTC) and non-medullary (NMTC), with familial cases being rare, especially in MTC (less than 1%) and NMTC (3-9%).
- A study analyzed the genetic data of 58 individuals from 18 Spanish families with familial NMTC and MTC, identifying 53 rare genetic variants in 12 families, some linked to known TC-associated genes.
- The findings suggest potential new genes associated with TC and highlight biological processes important for cancer development, paving the way for early detection, personalized treatments, and improved patient care.
Background: Up to 30% of differentiated thyroid cancer (DTC) will develop advanced-stage disease (aDTC) with reduced overall survival (OS).
Objective: The aim of this study is to characterize initial diagnosis of aDTC, its therapeutic management, and prognosis in Spain and Portugal.
Methods: A multicentre, longitudinal, retrospective study of adult patients diagnosed with aDTC in the Iberian Peninsula was conducted between January 2007 and December 2012.