Localized Nanoscale Formation of Vanadyl Porphyrin 2D MOF Nanosheets and Their Optimal Coupling to Lumped Element Superconducting Resonators.

A strategy toward the realization of a quantum spin processor involves the coupling of spin qubits and qudits to photons within superconducting resonators. To enable the realization of such hybrid architecture, here we first explore the design of a chip with multiple lumped-element LC superconducting resonators optimized for their coupling to distinct transitions of a vanadyl porphyrin electronuclear qudit. The controlled integration of the vanadyl qudit onto the superconducting device, both in terms of number and orientation, is then attained using the formation of nanosheets of a 2D framework built on the vanadyl qudit as a node.

Dilute Gd hydroxycarbonate particles for localized spin qubit integration.

Molecular spins are considered as the quantum hardware to build hybrid quantum processors in which coupling to superconducting devices would provide the means to implement the necessary coherent manipulations. As an alternative to large magnetically-dilute crystals or concentrated nano-scale deposits of paramagnetic molecules that have been studied so far, the use of pre-formed sub-micronic spherical particles of a doped Gd@Y hydroxycarbonate is evaluated here. Particles with an adjustable number of spin carriers are prepared through the control of both particle size and doping.

Challenges and recommendations for magnetic hyperthermia characterization measurements.

Purpose: The localized heating of magnetic nanoparticles (MNPs) the application of time-varying magnetic fields - a process known as magnetic field hyperthermia (MFH) - can greatly enhance existing options for cancer treatment; but for broad clinical uptake its optimization, reproducibility and safety must be comprehensively proven. As part of this effort, the quantification of MNP heating - characterized by the specific loss power (), measured in W/g, or by the intrinsic loss power (), in Hm/kg - is frequently reported. However, in / measurements to date, the apparatus, the analysis techniques and the field conditions used by different researchers have varied greatly, leading to questions as to the reproducibility of the measurements.

Anisotropic self-assemblies of magnetic nanoparticles: experimental evidence of low-field deviation from the linear response theory and empirical model.

The heating ability upon application of an alternating magnetic field of a system of monodisperse and non-interacting superparamagnetic nanoparticles is described by Rosensweig's model within the linear response limits. But in real applications, nanoparticle systems are rarely monodisperse or non-interacting, and predicting their heating ability is challenging, since it requires considering single-particle, inter-particle and collective effects. Herein we give experimental evidence of a collective effect that invalidates the linear response limits in self-assembled anisotropic arrangements.

Removal and insertion of central venous catheters in cancer patients is associated with high symptom burden.

Objectives: To assess the symptom burden associated with CVC removal and insertion in cancer patients.

Methods: We collected patient-reported symptom-burden outcomes for 60 consecutive cancer patients: 30 undergoing CVC removal and 30 undergoing CVC insertion. Cancer patients self-administered the MD Anderson Symptom Inventory to rate the severity of 21 different symptoms immediately after the procedure Results: Symptoms were present in up to 57% to 67% of patients undergoing CVC insertion and removal respectively.