Publications by authors named "E Nappi"

Background: Allergen immunotherapy (AIT) is the only treatment that modifies the natural course of allergies. However, AIT is only used in some eligible patients, is frequently underused, and only a few studies investigated this aspects. Understanding AIT utilization patterns might disclose information about why it is underused, thus providing valuable insights on how to broaden the positive impact it can have on the population.

View Article and Find Full Text PDF

Purpose Of Review: Advances in understanding the molecular pathways underlying nasal epithelial inflammation have ushered in the era of personalized medicine for chronic rhinosinusitis with nasal polyps (CRSwNP). Research progress has led to the approval of several monoclonal antibodies (mAbs) for severe CRSwNP, demonstrating promising outcomes in both clinical trials and real-world settings. Similarly, evolution in surgical techniques has enhanced progression-free survival due to the development of novel approaches.

View Article and Find Full Text PDF
Article Synopsis
  • Systemic sclerosis (SSc) has a notable link to an increased risk of cancer, with a study revealing a 20% overall prevalence of cancer among 290 SSc patients, including 8% classified as cancer-associated scleroderma.
  • The study found that older patients and those with specific autoantibodies (anti-Ro52 or anti-U3-RNP) were more prone to both cancer and cancer-associated scleroderma.
  • Additionally, cancer surveillance is crucial for patients with diffuse SSc, especially those who are older and lack classic SSc autoantibodies, as they have a higher risk for certain cancers, like breast cancer.
View Article and Find Full Text PDF
Article Synopsis
  • The Letter reports the most accurate measurement so far of the matter-antimatter imbalance during Pb-Pb collisions at a high energy level of 5.02 TeV.
  • It utilizes the Statistical Hadronization framework to determine precise values for the electric charge and baryon chemical potentials, μ_{Q} and μ_{B}.
  • The analysis of antiparticle-to-particle yield ratios shows that the collisions create a system that is generally baryon-free and electrically neutral at midrapidity.
View Article and Find Full Text PDF