Advanced Characterization of Solid-State Battery Materials Using Neutron Scattering Techniques.

Advanced batteries require advanced characterization techniques, and neutron scattering is one of the most powerful experimental methods available for studying next-generation battery materials. Neutron scattering offers a non-destructive method to probe the complex structural and chemical processes occurring in batteries during operation in truly in situ/in operando measurements with a high sensitivity to battery-relevant elements such as lithium. Neutrons have energies comparable to the energies of excitations in materials and wavelengths comparable to atomic distances in the solid state, thus giving access to study structural and dynamical properties of materials on an atomic scale.

Climbing the longevity pyramid: overview of evidence-driven healthcare prevention strategies for human longevity.

Longevity medicine is an emerging and iterative healthcare discipline focusing on early detection, preventive measures, and personalized approaches that aim to extend healthy lifespan and promote healthy aging. This comprehensive review introduces the innovative concept of the "." This conceptual framework delineates progressive intervention levels, providing a structured approach to understanding the diverse strategies available in longevity medicine.

Small-molecule disruption of androgen receptor-dependent chromatin clusters.

Sustained androgen receptor (AR) signaling during relapse is a central driver of metastatic castration-resistant prostate cancer (mCRPC). Current AR antagonists, such as enzalutamide, fail to provide long-term benefit for the mCRPC patients who have dramatic increases in AR expression. Here, we report AR antagonists with efficacy in AR-overexpressing models.

Validation of capture reactions cross sections in Cf(s.f.) neutron field.

We have investigated following capture reactions: Au(n,g)Au, Cu(n,g)Cu, Sc(n,g)Sc, Ta(n,g)Ta, Ce(n,g)Ce, La(n,g)La, Yb(n,g)Yb, Mn(n,g)Mn, and Pr(n,g)Pr in a standard Cf(s.f.) neutron field.

The impact of cross-linker distribution on magnetic nanogels: encapsulation, transport and controlled release of the tracer.

Magnetic nanogels (MNGs) are highly attractive for biomedical applications because of their potential for remote control of the rheology and internal structure of these soft colloids with biocompatible magnetic fields. In this contribution, using molecular dynamics simulations, we investigate the impact of the cross-linker distribution in the body of a MNG on the shape and magnetic response to constant and AC magnetic fields and relate those properties to the behaviour of non-magnetic tracers placed in the MNGs and left to escape. We find that if no AC magnetic field is applied, although the escape times of the tracer particles barely depend on morphology, the highest degree of subdiffusion is observed for the gels with a non-uniform cross-linkerer distribution.