[Side effects of new antiepileptic drugs in children, pregnant women and elderly patients].

The article discusses main side effects of new antiepileptic drugs in children, pregnant woman and old patients. Although, data related to these patients are not complete enough, new antiepileptic drugs offer some advantages in terms of tolerability, and less side effects in comparasion with drugs of the first and second generation.

[Fusion of negatively-charged liposomes under the effect of peptides from the N-terminal fragment of the HIV-1 transmembrane protein].

The effect of a series of synthetic peptides mimicking the N-terminus of HIV transmembrane glycoprotein (gp41) on fusion of negatively charged liposomes consisting of phosphatidylcholine, phosphatidylethanolamine and cardiolipin at a 2:3:5 molar ratio, respectively, has been studied. Peptides P514 and P385 (residue 517-538), lysine and arginine at the C-terminus, respectively, with the amino acid sequence completely corresponding to the N-terminus of gp41 displayed the highest fusogenic activity. The extent of fusion was significantly increased at mild acidic pH (6.

[Sanitary-protective and limitation areas for antennae of the decameter range].

A detailed overview of a transmitting antenna of the decameter range is provided. It is shown that the field near such antennas has rather a complex structure. A comparative analysis of the existing design techniques for the determination of electromagnetic field intensity has been undertaken.

[The analgesic activity of coordination compounds of methionine enkephalin with divalent metals].

Coordination compounds of methenkephalin with transition metals: copper, cobalt, nickel and zinc were shown to be superior to morphine by the analgesic activity and to morphine and methenkephalin by the duration of the analgesic effect. A more stable relationship between opiate receptors and copper-containing methenkephalin was shown in the experiments on the isolated neuronal membrane.