Publications by authors named "E N Ramsay"

The severity of MeV infection has been greatly reduced by the development of a live attenuated vaccine, which has been incorporated into vaccination programs in many countries. However, poor access to health facilities, and above all, the increase in anti-vaccination movements, has prevented the achievement of sufficient vaccination coverage. In outbreak scenarios, a rapid and transportable method can improve differential diagnosis, including removing ambiguity in suspected measles cases, contacts, or a cohort.

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Influenza infection represents a serious challenge for virological surveillance and healthcare systems in all countries globally. Despite obvious success in control of influenza through vaccination and antiviral drug development, this infection remains poorly controlled due to antigenic drift and fast selection of drug-resistant viral variants. The design of novel drugs with alternative targets and mechanisms of action is, therefore, an important goal for medical science worldwide.

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Russia is a country with a high incidence of tick-borne encephalitis (TBE). In northwestern regions of Russia, 110 TBE cases were registered in 2021. The largest numbers of TBE cases were registered in the Arkhangelsk region and St.

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RNA polymerase III (Pol III) transcribes short, essential RNAs, including the U6 small nuclear RNA (snRNA). At U6 snRNA genes, Pol III is recruited by the snRNA Activating Protein Complex (SNAPc) and a Brf2-containing TFIIIB complex, forming a pre-initiation complex (PIC). Uniquely, SNAPc also recruits Pol II at the remaining splicesosomal snRNA genes (U1, 2, 4 and 5).

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Article Synopsis
  • Patients experiencing post-anoxic status epilepticus (PASE) after cardiac arrest face poor outcomes due to a combination of therapeutic nihilism and the difficulty in managing their seizures, which creates a bleak outlook.
  • This negative cycle is exacerbated by the exclusion of hypoxic-ischemic causes from clinical trials, limiting the development of effective treatments for these patients.
  • Early treatment with vigabatrin, which inhibits the breakdown of GABA, shows promise as it may enhance the effectiveness of other GABA-targeting medications in managing PASE.
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