[The efficacy and safety of intra-articular application of a combination of sodium hyaluronate and chondroitin sulfate for osteoarthritis of the knee: a multicenter prospective study].

Unlabelled: in 3 mL on patients with knee osteoarthritis (OA) in a multicenter prospective study.

Materials And Methods: 79 outpatients (predominantly females 81.0%) from 5 RF constituent territories with primary tibiofemoral KellgrenLawrence score grade II or III knee OA, 40 mm pain intensity during walking on visual analogue scale (VAS), requiring NSAIDs intake (for at least 30 days during 3 months prior to enrollment) were included into the study after signing the informed consent form.

[Spondyloarthritis: modern terminology and definitions].

Unlabelled: Aim to identify outdated terms and make changes to the terminology of spondyloarthritis.

Materials And Methods: At the first stage of the work, the terms divided into two categories: "outdated" definitions and terms that need to be improved or unified. Subsequently, each member of the Expert Group of Spondyloarthritis at the Association of Rheumatologists of Russia (ExSpA) presented by its own definition of the designated term or agreed with the previous term.

Factors affecting the results of analgesic therapy. Results of the Russian multicentre study of NOTE (NSAID: Open-label Trial of Efficacy).

Aim: To identify factors affecting the effectiveness of NSAIDs in patients with OA and LBP.

Materials And Methods: An observational study was conducted to evaluate the effectiveness of a 2-week course of NSAIDs in OA and LBP in real clinical practice. The study group consisted of 3604 patients with OA and LBP (60.

[Analysis of the state-of-the-art of consulting medical care to patients with glucocorticoid-induced osteoporosis or its risk according to the data of a questionnaire survey (GLUCOST study)].

Aim: To analyze the state-of-the-art of consulting medical care to Russian patients with glucocorticoid-induced osteoporosis (GCOP) or its risk.

Subjects And Methods: This GLUCOST study was organized and conducted by the Russian Association of Osteoporosis. A total of 1129 patients with chronic inflammatory diseases, who had been taking oral glucocorticosteroids (OGCSs) a long time (3 months or more), were examined.

[Arterial rigidity, a marker of cardiovascular diseases].

Rigidity of the arterial wall is a generally accepted marker of cardiovascular diseases. Many studies are designed to investigate arterial rigidity in patients with arterial hypertension, coronary heart disease, and diabetes mellitus. The authors consider pathophysiological mechanisms underlying the enhancement of vascular rigidlity and the respective contributing fiactors, such as extensibility compressibility elasticity modulus, pulse wave propagation velocity, and augmentation index.