Publications by authors named "E N Oechslin"
Article Synopsis
- The study investigates the effectiveness of intracardiac echocardiography (ICE) in improving catheter ablation outcomes for ventricular tachycardia (VT) in adults with repaired tetralogy of Fallot (TOF).
- Results showed that ICE significantly enhanced isthmus localization and ablation success rates, but did not improve long-term freedom from VT or affect overall procedural times and complications.
- The conclusion emphasizes that while ICE is beneficial for tailored ablation based on individual anatomy, it does not lead to better long-term patient outcomes for VT in the context of repaired TOF.
Article Synopsis
- Rastelli surgery is performed to correct congenital heart defects, but late-onset cardiac arrhythmias are a notable complication, and there's limited data on their occurrence after this surgery.
- In a study of 55 patients followed for over 24 years, 38.4% experienced tachyarrhythmias, with older age at surgery linked to a higher risk; 21.8% had bradyarrhythmias, and some required catheter ablation.
- The results indicate that arrhythmia prevalence is significant and increases with age post-surgery, emphasizing the need for long-term monitoring in patients who underwent Rastelli surgery.
Background: Congenital heart disease (CHD) is the most common congenital anomaly. Almost 90% of isolated cases have an unexplained genetic etiology after clinical testing. Non-canonical splice variants that disrupt mRNA splicing through the loss or creation of exon boundaries are not routinely captured and/or evaluated by standard clinical genetic tests.
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- The study examines the long-term outcomes and reintervention rates in patients who underwent repair of Tetralogy of Fallot (TOF) using two different surgical techniques: valve sparing repair (VSR) and transannular patch (TAP), over a 30-year period.
- Results indicate that while survival rates are similar between the TAP and VSR cohorts, TAP patients experience significantly higher procedural burdens, with a greater need for multiple reinterventions and surgical pulmonary valve replacements.
- The findings emphasize that the choice of surgical method affects post-operative challenges, with TAP leading to more complications, while VSR shows an increased risk of reoperation for right ventricular outflow tract obstruction.
Vascular Ehlers-Danlos syndrome (vEDS) is a rare and aggressive heritable aortic disease caused by pathogenic variants in COL3A1 gene, characterized by spontaneous arterial dissection and organ rupture. The purpose of this study is to evaluate ventricular size and function and to explore their associations with complications in vEDS. Adults with genetically confirmed vEDS who underwent clinical cardiac MRI were retrospectively compared with controls matched for age and sex.
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