[Polyoxidonium in the treatment of calculous pyelonephritis].

Efficacy of polyoxidonium was studied in combined therapy of urolithiasis complicated with secondary pyelonephritis. Of 60 patients with secondary pyelonephritis in urolithiasis, 30 received adjuvant polyoxidonium. Phospholipids and cholesterol in cytomembranes were defined with thin-layer chromatography.

[Cardiogenic disorders of the systemic hemodynamics in lesions of the major cerebral arteries].

Evans blue dilution and ultrasound dopplerography was used to examine 170 atherosclerosis patients with initial manifestations of insufficient cerebral blood supply (77 patients) and transient disorders of the cerebral blood circulation (93 patients) with occlusive and stenotic involvements of the major brain arteries. The authors revealed characteristic aspects of responses of the systemic-hemodynamic mechanisms in initial manifestations of insufficiency of the cerebral blood supply and transient disorders of the cerebral blood circulation with stenosis and occlusions of the major brain arteries and without involvement of the brain vessels. Treatment aspects are discussed.

[Treatment of patients with transient disorders of cerebral circulation in occlusive diseases of major blood vessels of the head using vasoactive and cardiotonic drugs].

Transient circulatory disorders of the brain arising in response to stenosis and occlusion of the major head arteries in 111 patients were treated with cardiotonic and vasoactive drugs (corglycon, strophanthin, sulfocamphocain, euphylline++, cavinton, finoptin). The treatment was controlled by monitoring systemic and cerebral hemodynamic parameters. An appreciable clinical response was achieved in more patients (by 16.

[Vasoactive and cardiotonic drugs in the treatment of initial manifestations of cerebrovascular insufficiency in occlusive diseases of major blood vessels of the head].

Patients (n = 118) with initial manifestations of brain blood supply failure induced by stenoses and occlusions of the main vessels of the head were treated by cardio- and vasoactive drugs (corglycon, strophanthin, sulfocamphocaine, euphylline, cavinton, verapamil) under control of the systemic (by Evans blue dilution according to Stewart-Hamilton) and cerebral (by rheoencephalography and ultrasound dopplerography) hemodynamics. As a result of such treatment policy, the number of cases with a complete reverse development of the symptomatology was 16.8% greater than in analogous situations where no therapy with the method proposed was carried out.