Objective: To analyse the status of vitamin D and the influence of a supplement of vitamin D in neonates and infants during the first 6 months of life in the african equatorial environnement of Gabon.
Design: Clinical (weight, height, head circumference, and diseases) and biological (calcemia, phosphatemia, serum alkaline phosphatase activity and plasma 25-hydroxyvitamin D levels) parameters were compared between 2 groups of children: group 1: 41 infants receving a daily supplement of 1000 IU of vitamin D, and group 2: 38 infants without vitamin D supplement.
Results: No significant differences were observed between the 2 groups concerning clinical and biological parameters.
The efficacy and tolerance of artemether administered intramuscularly twice daily (1.6 or 3.2 mg/kg/day) were evaluated in 47 children (mean age 2.
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