Molecular mechanisms underlying thrombosis in systemic lupus erythematosus - A Systematic review.

Patients with systemic lupus erythematosus (SLE) face an approximately 30 % risk of thrombosis post-diagnosis. However, there remains significant knowledge gaps regarding causative mechanisms, and there is a lack of specific antithrombotic guidelines. This systematic review aims to examine the existing literature regarding the mechanisms contributing to thrombosis risk in SLE, focusing on five predefined procoagulant domains: autoantibodies (including antiphospholipid antibodies (aPL)), the complement system, platelets, the endothelium, and the coagulation system.

Risk of cervical stenosis after cervical excision in postmenopausal patients.

Objective: Cervical excision may cause cervical stenosis, leading to suboptimal follow-up of dysplasia and delayed diagnosis of cervical and endometrial pathology. This study aimed to quantify the risk of stenosis development after electrosurgical cervical excision in postmenopausal patients.

Methods: Retrospective cohort study based on data collection from electronic medical records and the Danish National Pathology Data Bank.

Early diagnosis of rheumatoid arthritis: associations between patients' perceptions of initial symptoms and the timing of seeking help from the general practitioner.

Objectives: Early diagnosis is essential to the prognosis of rheumatoid arthritis (RA), but little is known about patients' perceptions of the first symptoms. Illness representations shape patients' help-seeking behaviour. The Illness Perception Questionnaire - Revised (IPQ-R) can measure these, allowing us to understand the patients' role in diagnostic delays.

[Syphilis as a cause of intrauterine fetal death].

Syphilis is a rising concern in Denmark. In pregnancy, it can lead to congenital malformations, preterm birth, and intrauterine fetal death. We present a case where fetal death was diagnosed at gestational age 37.