[Comparative characteristic of clinical efficacy of the original drug Movalis and its generic Amelotex in the treatment of non-specific lumbar pain].

Objective: To perform a comparative analysis of the efficacy of the original drug meloxicam (movalis) and its generic (amelotex) in the treatment of patients with lower back pain.

Materials And Methods: The analysis of treatment results of 112 (61 men and 51 women) employees of JSC «Admiralteyskie Verfi», aged 18 to 60 years, was carried out. All these patients were treated in the period from 2015 to 2017 at the Medical Center of JSC «Admiralteyskie Verfi» due to dorsalgia of lumbosacral localization (ICD-10, item M54).

[MRI morphometry of neuroplastic changes in the brain after conservative treatment of traumatic brachial plexopathy].

Aim: To identify neuroplastic changes in the brain structures during treatment of traumatic axonotomy of the brachial plexus (the pathology of peripheral nervous system).

Material And Methods: MRI morphometry of white and grey matter was studied in 62 patients with traumatic axonotomy of the brachial plexus.

Results: There were correlations between the thickness of sensorimotor cortex, morphometric parameters (volume, diffusion, fractional anisotropy) of subcortical formations (corticospinal tracts, the forceps minor), severity of neurological deficit and dynamics of clinical course depending on the therapeutic strategy.

[The role of cholinesterase inhibitors in optimization of brain`s vascular pathology treatment (theoretical basis and clinical phenomenology)].

Cholinergic system of mediation is the most prevalent in the human body. Acetylcholine provides interaction of neurons in the central nervous system and transmission of nerve impulses from the peripheral neurons to the effectors. The results of the recent studies have demonstrated the significance of cholinergic system dysfunction in development of different neurological diseases.