Publications by authors named "E N Faure"
Introduction: The increase in the population of immunocompromised patients due to advances in management of end-stage diseases and transplants poses challenges in treating infections caused by multi-drug resistant (MDR) pathogens. Cefiderocol (FDC), a siderophore cephalosporin, has shown efficacy against carbapenem-resistant Gram-negative bacteria.
Methods: This retrospective multicentre study investigated the real-world use of FDC in 114 immunocompromised adults treated for MDR infections in 12 French hospitals (June 2020-November 2023).
Calcification of tissues involves the formation and deposition of calcium-containing crystals in the extracellular matrix (ECM). While this process is normal in bones, it becomes pathological when it occurs in cardiovascular and musculoskeletal soft tissues. Pathological calcification (PC) triggers detrimental pathways such as inflammation and oxidative stress, contributing to tissue damage and dysregulated tissue biomechanics, ultimately leading to severe complications and even death.
View Article and Find Full Text PDFAssociation between chronic long-term exposure to airborne dioxins and breast cancer.
Int J Hyg Environ Health
January 2025
Article Synopsis
- Breast cancer is the most common cancer in women, and environmental pollutants, particularly endocrine disruptors like dioxins, may influence its development.
- A study analyzed the link between airborne dioxin exposure and breast cancer risk in a cohort of 5222 cases and 5222 controls, using data about their proximity to dioxin sources and other factors.
- The results indicate a slight increase in breast cancer risk with higher cumulative dioxin exposure, suggesting the need for measures to reduce air pollution exposure.
Background: Growing epidemiological evidence suggests an association between exposure to air pollutants and breast cancer. Yet, the underlying mechanisms remain poorly understood. This study explored the mediating role of thirteen metabolic health biomarkers in the relationship between exposure to three air pollutants, i.
View Article and Find Full Text PDFObjective: To estimate the incidence of hospitalization with a diagnosis of herpes zoster (HZ) and post-herpetic neuralgia (PHN) in France between 2013 and 2020, overall and stratified by age-group and immune status.
Methods: Retrospective observational, database study, using the French hospital discharge database, which includes private and public data for all day-care and inpatient stays. Adults aged ≥18 years, hospitalized between January 1, 2013, and December 31, 2020, with a diagnosis of HZ or PHN, were included.