: Co-Design of a Novel Approach for Engaging People with Dementia in Physical Activity.

Background: Promoting physical activity among people living with dementia is critical to maximise physical, cognitive and social benefits; yet the lack of knowledge, skills and confidence among health professionals, informal care partners and people with dementia deters participation. As the initial phase of a larger feasibility study, co-design was employed to develop a new model of community care, to facilitate the physical activity participation of older people living with mild dementia.

Methods: Co-design methodology was utilised with nine stakeholders (with experience in referring to or providing physical activity programs and/or contributing to policy and program planning) over three workshops plus individual interviews with four care partners of people with dementia.

Microfilaria in the Urine of a Dog with Concurrent Urinary Bladder Sarcoma.

A 12 yr old female spayed American Staffordshire terrier was referred for stranguria, pollakiuria, and concern for a mass in the trigone of the urinary bladder. A urinalysis and abdominal ultrasound were performed to further investigate the bladder mass. Nematode larvae were identified in the urine, termed microfilaruria, while a caudal abdominal mass was found on ultrasound impinging on the urethra.

Tetrodotoxin toxicity: an increasing threat.

A man aged in his sixties presented to the emergency department with vomiting, dizziness and generalised weakness preceded by perioral and peripheral paraesthesias for several hours. He did not speak English and was visiting from overseas. Examination revealed multidirectional nystagmus, subtle bilateral ptosis, marked bilateral upper limb dysmetria and heel-shin ataxia, with mild proximal limb weakness.

Diet and Immune Effects Trial (DIET)- a randomized, double-blinded dietary intervention study in patients with melanoma receiving immunotherapy.

Background: Gut microbiome modulation is a promising strategy for enhancing the response to immune checkpoint blockade (ICB). Fecal microbiota transplant studies have shown positive signals of improved outcomes in both ICB-naïve and refractory melanoma patients; however, this strategy is challenging to scale. Diet is a key determinant of the gut microbiota, and we have previously shown that (a) habitual high dietary fiber intake is associated with an improved response to ICB and (b) fiber manipulation in mice impacts antitumor immunity.

Impact of Dried Thyme Leaf Meal on Production Performance, Egg Quality and Blood Parameters of Laying Hens.

Background: The use of commercially extracted phytogenic compounds to maintain poultry health and productivity in the absence of in-feed antibiotics is prohibitively costly in developing countries.

Objectives: The goal of the study is to determine the effect of dietary supplementation with Thymus schimperi leaf meal (TLM) on production performance, egg quality and haemato-biochemical parameters of Bovan brown layers.

Methods: A total of 96 laying hens at 25 weeks of age were randomly assigned to 4 treatments with 6 replications each.