[Anti-infective activity of anti-influenza antibodies from human colostrum].

Antibodies against influenza virus of A, B serological types and PC-virus were detected in the colostrum collected after an epidemic. These antibodies belonged to the secretory IgA form. The secretory antibodies preparation made of colostrum, and its IgA fraction instilled intransally to mice and rats prevented the development of infection caused by 100--10 ID50/0.

[Modelling of influenza infection in mice inoculated by the aerosol method].

Modelling of experimental influenza infection was performed in an aerosol apparatus the main element of which was a glove box made of organic glass. Mice were infected by inhalation of a highly dispersed aerosol of influenza A2/Victoria/72 virus adapted to the mouse lungs. The aerosol was produced by means of a pneumatic atomizer.

[Participation of secretory antibodies in the protection from influenza].

Two collective bodies (319 persons in all) were under observation from October, 1974 to March, 1975 for the purpose of studying the problem on the participation of antibodies of the respiratory tract secretion in the protection from influenza virus, type A, infection. During the influenza epidemic outbreak there was revealed a reverse relationship between the antibody concentration in the nasal cavity secretion and the incidence of the disease, and also an interaction between the antibodies of the secretions and the serum in the influenza protection.