Publications by authors named "E Musial"

Article Synopsis
  • * The article introduces a new method called top-down drug discovery (TD), which involves searching through a large database of fungi to find genetic locations that produce molecules targeting specific human proteins, like cyclin-dependent kinases (CDKs).
  • * Researchers successfully discovered two new molecules that inhibit CDKs and improved one of them to enhance its selectivity and effectiveness, showcasing the potential of TD for developing innovative medicines.
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Introduction: Approximately 35% patients with papillary thyroid carcinoma (PTC) and 13% with follicular thyroid carcinoma (FTC) present with metastases of cervical lymph nodes (LNs) at the time of diagnosis. In addition, 15-20% of patients treated with total thyroidectomy develop, after an interval of five years, metastases to the neck LNs on ultrasound examination. Fine-needle aspiration biopsy (FNAB) represents the gold standard technique for the detection of cervical LNs metastases.

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Background & Aims: The motivations of patients who consult a homeopathic (GP-Ho) or conventional (GP-CM) general practitioner for supportive care during cancer treatment have not been widely studied. We investigated the reasons why cancer patients consult a GP-Ho versus a GP-CM for supportive care and the GPs' motivations for their prescriptions.

Methods: This observational survey was carried out in France between October 2008 and October 2011.

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It has been suggested that the impact of emotional expressions on the startle reflex is influenced by the intention communicated by the expression (e.g., the intention to attack).

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Vitamin D-binding protein (DBP) participates in the actin scavenger system, it is a carrier of vitamin D and its derivatives, it manifests the capacity to bind mainly monounsaturated and saturated fatty acids, it binds to the surface of several cells and enhances chemotactic activity of C5a of the complement. The present study was aimed at answering the question whether serum DBP level in mares is related to levels of this protein in colostrum and in serum of its progeny. For this purpose, sera from 77 mares, colostra from 72 mares and sera from 69 Thoroughbred foals were collected.

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