Publications by authors named "E Mouloudi"
Sacroiliac joint (SIJ) tuberculosis (TB) is an infrequent clinical entity, especially in developed countries. The symptoms are usually non-specific, and therefore it may mimic a variety of degenerative and non-degenerative diseases, hampering the diagnosis. An interesting case of SIJ infection with psoas abscess in a 77-year-old male is presented in the current article.
View Article and Find Full Text PDFBackground: Endotype classification becomes the cornerstone of understanding sepsis pathogenesis. Macrophage activation-like syndrome (MALS) and immunoparalysis are the best recognized major endotypes, so far. Interferon-gamma (IFNγ) action on tissue macrophages stimulates the release of the cytotoxic chemokine CXCL9.
View Article and Find Full Text PDFArticle Synopsis
- The report discusses a case of a 48-year-old patient with pre-extensively drug-resistant tuberculosis (XDR tb) who died from myocarditis following a complex treatment regimen.
- The patient's history of poor adherence to medication resulted in acquired resistance to both first- and second-line drugs, complicating her condition.
- This case highlights a potentially lethal side effect of drug treatment for resistant tb, urging clinicians to be vigilant about the risk of drug-induced myocarditis in similar patients.
Article Synopsis
- Researchers classified sepsis into four clinical phenotypes using a simplified algorithm based on six admission parameters in a study involving 1498 patients, including those with bacterial sepsis and severe COVID-19.
- The analysis found distinct characteristics and outcomes for the phenotypes, with Phenotype α showing low mortality risk and Phenotype δ having the highest mortality.
- The study concludes that this phenotyping method is effective for predicting outcomes in both bacterial sepsis and severe COVID-19, suggesting it could have important prognostic applications.