Assessing Syzygium Aromaticum: From Chemical Profiling to Antioxidant, Antistaphylococcal, and Biocompatibility Attributes.

Staphylococcal infections challenge current treatments due to adverse effects and drug resistance, prompting the exploration of plant-derived compounds for their promising properties. This study aimed to analyze Syzygium aromaticum essential oil (SA-EO), aqueous (AE-SA) and ethyl acetate (EAE-SA) extracts for antioxidant and antistaphylococcal effects against sensitive and resistant clinical isolates. Erythrocytes were used as model cells for biocompatibility.

Phytochemical analysis and immunomodulatory activities in vitro and in vivo of Aframomum melegueta K Schum seed extracts.

Aframomum melegueta K Schum (A. melegueta), an herbaceous plant renowned for its medicinal seeds, was investigated for its potential immunomodulatory effects in vitro and in vivo using ethanolic and methanolic extracts. The immunomodulatory effect was evaluated by measuring antibody titers using the agglutination technique, while anti-inflammatory activity was assessed in a carrageenan-induced mouse paw edema model.

Antitumoral activity of on colorectal and prostate cancer cell lines.

is a medicinal plant used in Moroccan popular medicine, which has been employed as a remedy attributed to its anti-inflammatory, antipyretic, antinociceptive, antidiabetic, neuroprotective, and antiparasitic properties. The aim of the present study was to investigate the antitumor activity of both the methanolic and aqueous extract of . The effects of increasing concentrations of aqueous and methanolic extracts on human colorectal cancer HT-29 and HCT116 cell lines and human prostate cancer PC3 and DU145 cell lines were examined on cell proliferation using MTT assay and cell cycle analysis.

An Update of Research Animal Models of Inflammatory Bowel Disease.

Inflammatory bowel disease (IBD) is a group of chronic disorders that includes two main disease forms, Crohn's disease, and ulcerative colitis. The understanding of the intestinal inflammation occurring in IBD has been immeasurably advanced by the development of the now numerous murine models of intestinal inflammation. The usefulness of this research tool in IBD arises from a convergence of underlying genetic susceptibility, immune system dysfunction, environmental factors, and shifts in gut microbiota.