Publications by authors named "E Mossello"

Background: Prevalence, correlates and outcomes of respiratory failure (RF) were never studied in large populations of older patients hospitalized in acute care medical settings. Little is known about the possible association between RF and delirium, and whether these two syndromes, alone or in combination, may affect short-term mortality.

Objectives: To investigate prevalence and features of RF, the association between delirium and RF, and their effect on short-term mortality.

View Article and Find Full Text PDF
Article Synopsis
  • Trazodone, an antidepressant often prescribed for insomnia, anxiety, and behavioral disorders, is the focus of a study aimed at understanding its prescription reasons, effectiveness, and side effects in older adults in long-term care facilities.
  • The study included feedback from 37 out of 74 participating long-term care facilities, analyzing data from 427 older adults, revealing that common reasons for prescribing trazodone included agitation, insomnia, and depression, with over 90% reporting it was effective.
  • While trazodone proved beneficial, the study identified falls as a key side effect, affecting 30% of participants, underlining the need for careful monitoring in elderly patients, especially those with dementia.
View Article and Find Full Text PDF
Article Synopsis
  • Hospital-at-home (HaH) services, like the "Gruppo di Intervento Rapido Ospedale-Territorio" (GIROT) in Florence, offer an alternative to traditional hospital care for older adults, potentially minimizing hospital admissions and complications.
  • A study of 391 patients (average age 88.4 years) revealed high mortality rates over 6 months (53.8%) and hospitalizations (37.9%), with predictors for 6-month mortality including age and severe disability.
  • The GIROT model demonstrates high patient satisfaction and suggests the need for tailored care plans for older patients at risk of complications.
View Article and Find Full Text PDF

Background And Aims: Few studies have evaluated frailty in older hypertensive individuals and the most appropriate tools to identify frailty in this population have yet to be identified. This study compared the performance of six frailty instruments in the prediction of 1-year functional decline in older hypertensive outpatients.

Methods: The HYPERtension and FRAILty in Older Adults (HYPER-FRAIL) longitudinal pilot study involved hypertensive participants ≥75 years from two geriatric outpatient clinics at Careggi Hospital, Florence, Italy, undergoing identification of frailty with four frailty scales (Fried Frailty Phenotype, Frailty Index [FI], Clinical Frailty Scale [CFS], Frailty Postal Score) and two physical performance tests (Short Physical Performance Battery [SPPB] and gait speed).

View Article and Find Full Text PDF

Backgroung: The early identification of cognitive disorder is a primary scope, because it could reduce the rate of severe cognitive impairment and thus contribute to reduce healthcare costs in the next future.

Aims: The present paper aimed to build a virtuous diagnostic path of cognitive impairment, highlighting all the professionalism that can serve this purpose.

Methods: The Delphi method was used by the experts, who reviewed the information available during each meeting related to the following topics: early diagnosis of cognitive impairment, definition of Mild Cognitive Impairment, unmet needs in post-stroke patients, critical decision-making nodes in complex patients, risk factors, neuropsychological, imaging diagnosis, blood tests, the criteria for differential diagnosis and the possible treatments.

View Article and Find Full Text PDF