Publications by authors named "E Morisbak"
Objective: Assess the biological and physicochemical properties of AH Plus, BioRoot RCS and Pulp Canal Sealer (PCS) leachates with and without chlorhexidine (CHX).
Methods: The sealers were studied in no contact and 1-minute contact with CHX. For biological properties (antibacterial activity and cytotoxicity), leachates were formed in saline of freshly mixed, 1-, 7- and 28 days set sealers.
Objective: To investigate the metal ion release, surface roughness and cytoxicity for Co-Cr alloys produced by different manufacturing techniques before and after heat treatment. In addition, to evaluate if the combination of materials affects the ion release.
Methods: Five Co-Cr alloys were included, based on four manufacturing techniques.
In vitro effects of dental monomer exposure - Dependence on the cell culture model.
Toxicol In Vitro
September 2020
Article Synopsis
- Methacrylate monomers are key components in resin-based biomaterials, but incomplete polymerization leads to leakage, posing risks to patients.
- The study investigated the effects of two methacrylates, 2-hydroxyethyl-methacrylate (HEMA) and hydroxypropyl-methacrylate (HPMA), on five different cell lines to evaluate their impact on cell viability, death, and other cellular responses.
- Results showed both methacrylates reduced cell viability and glutathione levels, but the response varied by cell line; however, no significant differences were found between the effects of HEMA and HPMA on these cell lines.
Methacrylate monomers, like 2-hydroxyethyl methacrylate (HEMA), are common components of resin based dental materials. Leakage of unpolymerized monomers after placement and curing leads to human exposure. HEMA is known to inhibit lipopolysaccharide (LPS) induced cytokine release.
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