Publications by authors named "E Mollo"
Article Synopsis
- Caulerpin (CAU) is a bioactive compound from invasive green algae, while caffeine (CAF) is a common water pollutant and psychoactive substance. Both can accumulate in aquatic life and in human diets.
- The study used mussels (Mytilus galloprovincialis) to explore potential interactions between CAU and CAF, finding that CAF induced toxic effects, but CAU did not worsen these effects or cause cumulative damage.
- The results suggest CAU may help reduce CAF toxicity due to its potential role in detoxification processes, encouraging more research into its possible use as a food additive for clearing pollutants from the body.
The occurrence of increased antibiotic resistance has reduced the availability of drugs effective in the control of infectious diseases, especially those caused by various combinations of bacteria and/or fungi that are often associated with poorer patient outcomes. In the hunt for novel antibiotics of interest to treat polymicrobial diseases, molecules bearing guanidine moieties have recently come to the fore in designing and optimizing antimicrobial agents. Due to their remarkable antibacterial and antifungal activities, labdane diterpenes are also attracting increasing interest in antimicrobial drug discovery.
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- Bioactive compounds from marine invasive species, like the alkaloid caulerpin (CAU) from the invasive green algae Caulerpa cylindracea, can have significant effects on native marine life, similar to the synthetic drug fenofibrate (FFB), which poses risks to aquatic ecosystems.
- A study comparing the effects of CAU and FFB on the mussel species Mytilus galloprovincialis showed that FFB resulted in metabolic impairments and cellular damage, while CAU did not lead to significant adverse effects.
- Findings suggest that while FFB is harmful and its release should be minimized, CAU could be a potential resource for utilizing invasive species without detrimental impacts on marine life.
Introduction: There are abundant studies on headache and migraine in women but few or none about their occurrence during labor, delivery, and postpartum (2 hours after delivery) owing to the low incidence. A headache attack can be debilitating when a woman is trying to manage labor pain. Research at our Women's Headache Center within the Department of Gynecology and Obstetrics has begun to shed light on this potential association.
View Article and Find Full Text PDFThe invasive macroalga has spread widely in the Mediterranean Sea, becoming a favorite food item for native fish for reasons yet unknown. By using a combination of behavioral, morphological, and molecular approaches, herein we provide evidence that the bisindole alkaloid caulerpin, a major secondary metabolite of , significantly increases food intake in the model fish , influencing the regulation of genes involved in the orexigenic pathway. In addition, we found that the compound improves fish reproductive performance by affecting the hypothalamus-pituitary-gonadal axis.
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