Publications by authors named "E Mokaddas"
Article Synopsis
- Recent outbreaks of multidrug-resistant fungi in healthcare settings highlight the need for effective antifungal susceptibility testing (AST) to manage invasive infections.* -
- The study compared the performance of Etest and broth microdilution-based MICRONAUT-AM-EUCAST assays by testing 121 clinical isolates, revealing significant discrepancies in fluconazole and amphotericin B resistance assessments.* -
- Findings suggest that MCN-AM underestimates fluconazole resistance, while Etest overestimates amphotericin B resistance, indicating a need for method-specific resistance breakpoints to improve clinical outcomes.*
Objective: Increasing reports of resistance to newer anti-tuberculosis drugs have prompted the search for other alternative drugs. Streptomycin could be used for the treatment of drug-resistant tuberculosis if susceptibility of Mycobacterium tuberculosis isolate to streptomycin could be accurately detected. We performed phenotypic and genotypic drug susceptibility testing (DST) of 118 M.
View Article and Find Full Text PDFBackground: Multilocus sequence typing (MLST) is used to gain insight into the population genetics of bacteria in the form of sequence type (ST). MLST has been used to study the evolution and spread of virulent clones of in many parts of the world. Such data for are lacking for the countries of the Arabian Peninsula, including Kuwait.
View Article and Find Full Text PDFCandida auris is an emerging, multidrug-resistant yeast, causing outbreaks in healthcare facilities. Echinocandins are the antifungal drugs of choice to treat candidiasis, as they cause few side effects and resistance is rarely found. Previously, immunocompromised patients from Kuwait with C.
View Article and Find Full Text PDFObjectives: To report antimicrobial resistance data for Gram-positive and Gram-negative pathogens isolated from paediatric patients in three hospitals in Kuwait during 2012-19.
Methods: activity of antimicrobials against isolates from documented infections was determined using CLSI broth microdilution method and breakpoints at a central laboratory. Enterobacterales and isolates were screened for β-lactamases using multiplex PCR assays.