Multidetector computed tomography angiography study of the renal arterial vasculature anatomy and its variations in a Bulgarian adult population.

Purpose: Renal arterial anatomy has a great clinical importance during surgical and endovascular procedures. However, comprehensive data on renal arterial variations in the Bulgarian population has not yet been provided. The aim of this study was to conduct a detailed research about the normal anatomy and variations of the renal arteries in the Bulgarian population.

Use of External Comparators for Health Technology Assessment Submissions Based on Single-Arm Trials.

Background: Single-arm trial (SAT) data is increasingly reviewed for drug approvals by regulators and Health Technology Assessment (HTA) bodies. Supplementary data in the form of external comparators (ECs) can be used to provide clinical context to support these drug evaluations. In this study we characterized HTAs for SAT-based submissions, the use of supplementary EC data and outcomes from HTA review.

Assessment of Anxiety and Depressive Symptoms in the Early Post-stroke Period.

Introduction: There is some evidence suggesting an association between cerebrovascular diseases and the development of depression on the one hand, and between depression and post-stroke recovery on the other. Post-stroke depression can occur in the early post-stroke period or in the later stages of recovery (over 9 months after the incident).

Aim: To find a connection between stroke and the development of anxiety and depression in the early period after the development of neurological deficit and to evaluate several scales for their potential usefulness in the screening of post-stroke patients for early signs of depression and anxiety.

Serialized holography for brand protection and authentication.

The problems presented by counterfeit products and documentation are discussed. Limitations of existing holograms for anti-counterfeit applications are described. We describe the advantages of full holographic serialization and the requirements in terms of materials and techniques for mass production of true serialized holograms.

Low-Toxicity Photopolymer for Reflection Holography.

A novel composition for a low-toxicity, water-soluble, holographic photopolymer capable of recording bright reflection gratings with diffraction efficiency of up to 50% is reported. The unique combination of two chemical components, namely, a chain transfer agent and a free radical scavenger, is reported to enhance the holographic recording ability of a diacetone acrylamide (DA)-based photopolymer in reflection mode by 3-fold. Characterization of the dependence of diffraction efficiency of the reflection gratings on spatial frequency, recording intensity, exposure energy, and recording wavelength has been carried out for the new low-toxicity material.