Publications by authors named "E Meli"
Fertility preservation in lymphoma patients treated with immunochemotherapy regimens with or without radiotherapy: results of a retrospective multicenter Italian study (Ferty care).
Leuk Lymphoma
October 2024
Article Synopsis
- - The study examined fertility preservation methods in 414 female lymphoma patients aged 18-40 diagnosed between 2010 and 2018, with most common cancer types being Hodgkin Lymphoma (74%) and various others.
- - Majority of the patients (71%) received ABVD as the first-line treatment, while fertility preservation strategies included GnRHa (78%), oral contraceptives, and cryopreservation of oocytes and ovarian tissue.
- - After treatment, 70% of women had regular menstrual cycles, 8% experienced premature ovarian failure, and there were 43 pregnancies observed during a median follow-up of 5 years, with age and treatment intensity being significant factors for amenorrhea and POF.
Article Synopsis
- Vaccinations play a crucial role in preventing infectious diseases, particularly for immunocompromised individuals like those with non-Hodgkin lymphomas (NHLs).
- The COVID-19 pandemic highlighted the need for effective vaccinations to prevent severe complications in NHL patients, but studies show reduced vaccine responses after treatment with anti-CD20 monoclonal antibodies.
- This review discusses the effectiveness of COVID-19 and other vaccines in NHL patients and suggests team-based strategies for better vaccine management in these individuals.
Article Synopsis
- Sentinel lymph node (SLN) biopsy for breast cancer patients after neoadjuvant chemotherapy is difficult due to a high false-negative rate, but using dual tracers and clipped lymph nodes (CLN) can improve results.* -
- A study of 73 patients showed a 98.6% identification rate for CLNs, with 59% achieving a complete response in lymph nodes, although some cases saw discrepancies between SLNs and CLNs.* -
- Targeted axillary dissection (TAD) proved to be more accurate than SLN alone, leading to changes in surgical or oncologic management for about 10% of patients, signaling the need for further research.*
In recent decades, the request for more efficient performances in the aeronautical sector moved researchers to pay particular attention to all the related mechanisms and systems, especially with respect to the saving of power. In this context, the bearing modeling and design, as well as gear coupling, play a fundamental role. Moreover, the need for low power losses also concerns the study and the implementation of advanced lubrication systems, especially for high peripheral speed.
View Article and Find Full Text PDFNodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is a rare entity whose neoplastic cells retain a B-cell phenotype with expression of CD20. Radiotherapy is recommended for favorable stage IA disease while for other stages guidelines suggest therapeutic strategies similar to those used for classic HL. The role of rituximab, although quite widespread, is not completely elucidated.
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