Joint effects of atrial fibrillation and prothrombotic genotypes on the risk of ischemic stroke.

Background: Atrial fibrillation (AF) is a major risk factor for ischemic stroke. Whether prothrombotic single nucleotide polymorphisms (SNPs) impact stroke risk in AF is not well known.

Objectives: To investigate the joint effects of five prothrombotic SNPs and AF on ischemic stroke risk.

Longitudinal cholesterol trends across socioeconomic groups in Norway: the influence of lipid-lowering drugs in the population-based Tromsø Study 1994-2016.

Objectives: There is limited evidence regarding the impact of lipid-lowering drugs (LLDs) on the socioeconomic gradient in a longitudinal perspective. The study investigates the longitudinal socioeconomic gradient in total cholesterol levels and whether this is affected by the use of LLDs.

Design: Population-based cohort study.

Geographical differences in thrombolysis treatment for acute ischaemic stroke.

Background: Administering intravenous thrombolysis (IVT) as soon as possible after symptom onset impacts on the functional outcome for patients with acute ischaemic stroke. The study aimed to assess whether the distance from hospital impacts on the access to IVT for acute ischaemic stroke at the University Hospital of North Norway in Tromsø (UNN Tromsø).

Material And Method: This prospective quality study included 231 patients admitted with acute ischaemic stroke to UNN in the period 1 January 2019-31 December 2019.

Effectiveness of a family-based health promotion intervention for women with prior GDM: The Face-it RCT.

Context: Gestational diabetes mellitus (GDM) increases the risk of future type 2 diabetes (T2DM), but effective and feasible interventions to reduce this risk are lacking.

Objective: To evaluate the effectiveness of a family-based health promotion intervention on T2DM risk factors and quality of life among women with recent GDM.

Design: Multicenter, parallel, open-label randomized controlled trial with 2:1 allocation ratio.