Publications by authors named "E Masson"
The CEL-HYB1 hybrid allele of the carboxyl ester lipase (CEL) gene and its pseudogene (CELP) has been associated with chronic pancreatitis (CP). Recent work indicated that amino acid positions 488 and 548 in CEL-HYB1 determined pathogenicity. Haplotype Thr488-Ile548 was associated with CP while haplotypes Thr488-Thr548 and Ile488-Thr548 were benign.
View Article and Find Full Text PDFPatients with hematologic malignancies (HM) are highly susceptible to bloodstream infection (BSI), particularly those undergoing treatments such as chemotherapy. A common and debilitating side effect of chemotherapy is oral and intestinal mucositis. These Patients are also at high risk of developing sepsis, which can arise from mucosal barrier injuries and significantly increases mortality in these patients.
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- The XENONnT dark matter experiment successfully measured nuclear recoils from solar ^{8}B neutrinos, marking a significant advancement in neutrino detection technology.
- Using a two-phase time projection chamber with a 5.9 t liquid xenon target, the experiment produced 37 observed events, which surpassed the expected background events, indicating a notable signal.
- The results provide a measured solar neutrino flux consistent with previous studies and confirm the neutrino cross section predictions aligned with the Standard Model, showcasing the effectiveness of dark matter detectors in neutrino research.
Macrocycles that encapsulate two guests can self-sort those into homo- and heterodimers. We report here a family of self-sorting homobimetallic Pt(II) terpyridyl acetylide dimers secured together with a pair of Cucurbit[8]uril macrocycles (CB[8]). The rigid bridging unit between both Pt centers introduces varying "hinge" angles, resulting in disparities in Pt-Pt distances in the heterodimers, and leads to recognition motif mismatch.
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- Researchers found a specific Alu insertion variant (Alu_Ins) in the SPINK1 gene, which causes severe pancreatic problems in infants by completely shutting down SPINK1 mRNA expression.
- Initial hypotheses suggested that this insertion might disrupt the formation of mRNA ends or other processes, but tests showed only a partial reduction in gene activity that didn't explain the severity of the condition.
- The study highlighted that structures formed by double-stranded RNA (dsRNA) between Alu elements likely contribute to the mRNA loss, suggesting that aligning these elements correctly could restore gene expression, with broader implications for understanding Alu insertions in genetic diseases.