Publications by authors named "E Martin-Orozco"
Article Synopsis
- The study investigates how polyamine levels during pregnancy are linked to maternal allergies and immune responses in newborns.
- Spermidine and spermine were found to be the main polyamines in both mothers and their newborns, with lower spermine levels associated with maternal allergic conditions, particularly allergic conjunctivitis.
- Higher levels of polyamines in cord blood correlated with an increased number of lymphocytes and reduced production of inflammatory and Th2-related cytokines, suggesting a potential protective effect against allergies in infants.
Background: Immune signatures at birth could be associated with clinical outcomes and will improve our understanding of immunity prenatal programming.
Methods: Data come from 235 newborns from the cohort study NELA. Production of cytokines was determined using Luminex technology.
Background: Outdoor air pollution may disturb immune system development. We investigated whether gestational exposure to traffic-related air pollutants (TRAP) is associated with unstimulated cytokine profiles in newborns.
Methods: Data come from 235 newborns of the NELA cohort.