Publications by authors named "E Marlinge"
Background: Patients with bipolar disorder (BD) are at increased risk of dementia. The underlying mechanisms are debated. FDG-PET elucidates glucose metabolic reductions due to altered neuronal activity in the cerebral cortex, allowing detection and identification of neurodegenerative processes.
View Article and Find Full Text PDFBackground: Quality of life is decreased in bipolar disorders (BD) and contributes to poor prognosis. However, little is known about the causal pathways that may affect it. This study aimed to explore health-related QoL (HRQoL) in BD and investigate its relationship with cognition and psychosocial functioning.
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- Bipolar disorder (BD) is a complex mental health condition, and researchers aimed to identify a neurodevelopmental phenotype (NDP) that contributes to its development and impacts clinical outcomes.
- By analyzing data from over 4,400 BD patients, they established nine specific clinical features that characterize this NDP, which are linked to poorer prognosis and treatment responses.
- The findings suggest that patients with a higher NDP load may have overlapping genetic factors with ADHD, indicating a potential shared biological basis for these disorders.
Article Synopsis
- - Psychosis, marked by delusions and hallucinations, is common in Alzheimer's and other neurodegenerative dementias, leading to challenges in diagnosis and treatment.
- - A systematic review of 98 studies reveals high prevalence rates of psychotic symptoms across different dementias, with notable patterns such as misidentification delusions in dementia with Lewy bodies and paranoid ideas in Alzheimer's.
- - The findings highlight significant variations in psychotic symptoms among different neurodegenerative diseases, emphasizing the need for more research on early-stage psychosis to improve diagnosis and management.
Bipolar disorders (BD) are characterized by cognitive impairment during the euthymic phase, to which treatments can contribute. The anticholinergic properties of medications, i.e.
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