Publications by authors named "E Mansilla"
Introduction: In emergency rooms (ERs), 5% of patients experiencing an acute ischemic stroke (AIS) receive an alternative diagnosis; these cases are known as stroke chameleons (SC). The percentage of SC treated with intravenous thrombolysis (IVT) and the characteristics have not been well described. We aimed at investigating the variables associated with the probability receiving IVT.
View Article and Find Full Text PDFBackground: Stroke chameleons (SC), are often diagnosed too late in their course to benefit from intravenous thrombolysis (IVT) treatment in the Emergency Room (ER). It remains unclear what proportion of this patient population would be a candidate for IVT. We sought to identify the proportion of SC patients with contraindications to IVT and to delineate what those contraindications are.
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- The 22q11.2 region is prone to genetic changes that can lead to several disorders, such as 22q11.2 microdeletion syndrome and Emanuel Syndrome.
- This study examines mortality rates, average age at death, and risk factors in 223 confirmed patients with 22q11.2 rearrangements, revealing that 21 (9.4%) of them died, predominantly in early childhood.
- Key findings show that 71.42% of deaths were due to cardiac causes, with a median age of death of 3 months and 18 days, contributing valuable data on mortality associated with these genetic disorders.
Introduction: Scarce data exist about clinical/radiological differences between acute ischemic strokes diagnosed in the emergency room (AISER) and stroke chameleons (SCs). We aimed at describing the differences observed in a comprehensive stroke center in Chile.
Methods: Prospective observational study of patients with ischemic stroke syndromes admitted to the emergency room (ER) of Clínica Alemana between December 2014 and October 2023.
Article Synopsis
- This study evaluates chromosomal abnormalities in fetuses with nuchal translucency (NT) measurements between 3.0 and 3.4 mm, which are often missed by non-invasive prenatal testing (cfDNA).
- A review of data from 271 fetuses revealed that 18.8% had chromosomal aberrations, with significant findings including common trisomies in 15% of cases and a small percentage involving sex chromosome aneuploidy.
- The research suggests that many fetuses at increased risk for chromosomal issues due to NT measurements may require invasive testing, as NIPT has limitations that could lead to false negatives.